Main Article Content
Background: Carpal tunnel syndrome (CTS) is the most commonly reported complication of dialysis-related amyloidosis in patients on long-term hemodialysis (HD) therapy. The aim of this literature review is to assess and present our current knowledge of the risk factors of CTS in patients on long-term hemodialysis.
Materials/Methods: A systematic search to gather the different risk factors of CTS reported in the literature was conducted using PubMed, Cochrane and Google scholar from 2008 to 2018. Key words and their combination were used, including carpal tunnel syndrome, hemodialysis and dialysis related amyloidosis.
Results: This study included 11 articles that met our criteria. Incidence of CTS in hemodialysis patients increased with the duration of dialysis, age of the patient, arteriovenous fistula, and β2-microglobulin deposition.
Conclusion: Several risk factors were identified, but a clear cause was not established. A multifactorial, complex interaction between some or all of the risk factors most likely exists and could explain the incidence of CTS in this population.